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Corpus Journal of Case Reports
[ ISSN : 2833-4388 ]


Amyloid Gallbladder as an Initial Presentation of Multiple Myeloma (MM): A Rare Presentation

Case Report
Volume 2 - Issue 1 | Article DOI : 10.54026/CJCR/1010


Madhuri Chengappa* and Thejaswi K Poonacha

1Department of Medicine, Nazareth Hospital, Pennsylvania
2Department of Internal Medicine, University of Minnesota Medical Center, Minnesota

Corresponding Authors

Madhuri Chengappa, Department of Internal Medicine, Nazareth Hospital, USA

Keywords

Cholecystitis; Amyloidosis; Multiple Myeloma

Received : November 15, 2021
Published : November 22, 2021

Abstract

We present a rare case of Amyloid (AL) deposition in the gallbladder as an initial presentation of MM. The patient was a 92-year-old female who was admitted to the hospital with right upper quadrant pain. Computed Tomography (CT) abdomen and pelvis showed stone in the distal common bile duct and mildly distended gallbladder with wall thickening, she underwent ERCP for stone extraction followed by cholecystectomy. A postoperative histological examination revealed congo red stain positive for amyloidosis, positive apple-green birefringence under polarized light, and was typed as AL. Further workup, showed a lytic bone lesion on the skeletal survey and bone marrow core biopsy showed hypercellular bone marrow with increased plasma cells confirming the diagnosis of MM