Corpus Journal of Dairy and Veterinary Science
[ ISSN : 2833-0536 ]
A Mini Review on Administrations of Trichuris Suis Ova as Therapy for Inflammatory Bowel Diseases
Abstract
Crohn’s disease and ulcerative colitis are two Inflammatory Bowel Diseases (IBD). They are marked by an abnormal response by the body’s immune system. Some of the response may be attributed to genetic predisposition, while environmental factors play a role as well. It has also been noted that in people in developing countries that have been exposed to helminths have a lower prevalence compared to people not exposed to helminths in industrialized countries. This may be due to the augmented immunological response to antigens that comes with the helminth exposure. Studies have been conducted to determine the safety and efficacy of intestinal helminth, Trichuris Suis Ova (TSO) as IBD therapy. The results are promising for TSO therapy as treatment for IBD, but further investigation is warranted to better substantiate the findings.