Loading

Global Journal of Infectious Diseases


Antiretroviral Therapy: A Compendium of the Evolving Treatment Paradigm for HIV infection

Review Article
Volume 2 - Issue 1 | Article DOI : 10.54026/GJID/1003

Ritin Mohindra1 , Rakavi R2 , Arushi Ghai3 , Roshan Mathew4 , Nanda Gamad5*, Tarun Narang6 and Praveen Aggarwal7

1Assistant Professor, Department of Internal Medicine, PGIMER, Chandigarh, India
2Junior Resident, Department of Internal Medicine, PGIMER, Chandigarh, India
3Junior Resident, Department of Community Medicine, LHMC, New Delhi, India
4Senior Resident, Department of Emergency Medicine, AIIMS, New Delhi, India
5Assistant Professor, Department of Pharmacology, PGIMER, Chandigarh, India
6Associate Professor, Department of Dermatology, Venereology and Leprology, PGIMER, Chandigarh,
India
7Professor and Head, Department of Emergency Medicine, AIIMS, New Delhi, India

Corresponding Authors

Nanda Gamad, Assistant Professor, Department of Pharmacology, PGIMER, Chandigarh, India

Keywords

Human Immunodeficiency Virus; Acquired Immunodeficiency Syndrome; ART Regimen; Dolutegravir

ABSTRACT

Guidelines on Antiretroviral Therapy (ART) are updated regularly and it is important to be abreast with the increasing knowledge. Recent international recommendation suggests initiating the ART to all those individuals who have detectable viremia. While it is imperative to perform baseline CD4+ counts, viral loads and resistance testing before starting treatment, non-availability of any of these tests should not delay treatment initiation. Currently, ART in the form of daily administered triple-drug combination therapy consisting of 2 NRTIs plus 1 INSTI/PI/NNRTI, is recommended for newly diagnosed patients. The regimen should be selected based on virological efficacy, adverse effects, drug-drug interactions and cost. This article is an attempt to give an overview of existing and upcoming antiretroviral drugs and recent recommendations in the management of people living with human immunodeficiency virus infection.

Received : June 01, 2022
Published : June 13, 2022

Journals

Corpus Journal of Surgery
ISSN : Short Title : CJS
World Journal of Food and Nutrition
ISSN : Short Title : WJFN
Concepts in Neurology and Research
ISSN : Short Title : CNR
Current Research in Emergency Medicine
ISSN : 2832-5699 Short Title : CREM
Global Journal of Pediatrics
ISSN : Short Title : GJP
Current Trends in Engineering Science
ISSN : Short Title : CTES