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Advance Research in Organic and Inorganic Chemistry
[ ISSN : 2833-3594 ]


Characterizations of Liquid Crystals as A Transdermal Drug Delivery System

Mini Review
Volume 3 - Issue 2 | Article DOI : 10.54026/AROIC/1013


Wesam R Kadhum1*, Saeed AS Al-Zuhairy1 , Radhi K Obaid1 , Muqdad Alhijjaj2,3

1Department of Pharmacy, Kut University College, AL Kut, Wasit, 52001, Iraq
2Department of Pharmaceutics, College of Pharmacy, University of Basrah, Basrah 61004, Iraq
3Department of Pharmacy, Al-Kunooze University College, Basrah 61029, Iraq

Corresponding Authors

Wesam R Kadhum, Ph.D, Department of Pharmacy, Kut University College, AL Kut, Wasit 52001, Iraq, Telephone No: 00964-782-825-5935 (Iraq); 0081-80- 9462-0134 (Japan)

Keywords

Pluronic Copolymers; Drug Delivery Systems; Solid Crystals; Drug Diffusivity; Keratinocytes Cells; Biocompatibility

Received : September 09, 2022
Published : October 06, 2022

Abstract

The outermost layer of skin, the stratum corneum, has a role as the primary barrier against water evaporation from the body and drug entry through skin into the body. Thus, overcoming the stratum corneum barrier is important to develop transdermal drug delivery systems. Transdermal administration of drugs represents an excellent alternative to conventional pharmaceutical dosage forms. However, insufficient penetration of the active pharmaceutical substance through the skin is a common problem. Thus, in the present review we discussed the characterizations and the skin permeation enhancing ability of liquid crystal (LC) topical formulations.