Advance Research in Organic and Inorganic Chemistry

Green Techniques to Synthesize Schiff Bases

Mini Review
Volume 3 - Issue 2 | Article DOI : 10.54026/AROIC/1011

Atul R Bendale* , Manali Borse, Laxmikant Borse, Vasim Pathan, Anil Jadhav

Sandip Institute of Pharmaceutical Sciences, Nashik, 422213 (M.S) India

Corresponding Authors

Atul R Bendale, Associate professor, Department of Pharmaceutical Chemistry, Sandip Institute of Pharmaceutical Sciences, Nashik, 422213 (M.S) India. Mob No: +91 8000701337


Schiff Bases; Imines; Green Synthesis; Sonochemistry; Mechanochemistry; Microwave Assisted Synthesis


From ancient times, the chemistry of Schiff base-containing molecules has been a fascinating subject of study. They've been found to be a flexible pharmacophore for the creation and development of a wide range of bioactive lead compounds. Schiff bases are compounds containing the imine functional group. Different Schiff base containing byproducts have recently been synthesized and studied for activities such as antioxidant, antibacterial, antituberculosis, anti-inflammatory, antidepressant and anxiolytic activity, antihypertensive, anticonvulsants, anticancer, and antifungal activity. Different green chemistry techniques like-solid state, sonochemical, microwave assisted synthesis for synthesis of Schiff bases are discussed in this review.