Odontogenic keratocysts are lesions that derive from the epithelial remains of the dental lamina, they have slow growth, they are aggressive as they are expansive and highly recurrent, they may or may not be associated with syndromes, they have a higher incidence in the 2nd decade of life and may have another peak. between 55-65 years; There is a certain predilection for the male gender, the differential diagnosis is broad both clinically and radiographically. It can be managed with conservative treatment (enucleation, curettage, cryotherapy, chelating agents) or aggressive management (bloc or marginal resection). The objective of the present study is to introduce silicone valve decompression as part of the treatment of odontogenic keratocysts, since there are not enough studies in this regard in Mexico. We present a case of a patient with an Odontogenic Keratocyst, treated by the Maxillofacial Surgery service of the “La Raza” Medical Center, who underwent decompression with a silicone valve. The long-term result is presented by radiographic control after three years without reporting complications or recurrence.