Bangladesh University of Engineering & Technology (BUET)’s Chemical Engineering Department is almost 75 years old. This department has one the world’s best Chemical Engineering curriculums to teach enrolled bright students of the country. As result, the students can grab the teaching materials easily to educate themselves. Despite this, the graduates face many challenges to establish themselves in home and abroad. Competitive curriculum and personal competency are the strength. Lack of quality facility and resources are the weakness. Innovative quality and devotion in profession are the opportunity. Social, cultural, environmental and economic issues are the threat of the graduates of this department in home and abroad. Some graduate can overcome these issues while the other cannot. Those who can overcome, become success. Lack of prior knowledge on many issues is the main cause of failure in working career. Proper knowledge on many issues and compatible aptitude help the graduates to overcome many challenges in order to establish themselves in home and abroad.