T here is currently significant public alarm about presence of PFAS in the environment because these chemical species are persistent and some have been shown to be deleterious to the health of living organisms. This concern has been extended to some fluorinated refrigerants, including R-1234ze(E), because some of these can partially degrade in the atmosphere to Trifluoroacetic acid (TFA), which some agencies classify as a PFAS. However, a review of authoritative independent opinion reveals that TFA at concentrations that are currently present in the environment, or are likely to pertain for the remainder of this century, do not, and will not, reach levels which pose a threat to within several orders of magnitude. The reason that TFA is toxicologically benign is that, unlike its longer chain Perfluoro carboxylic acid cousins, it does not readily adsorb to surfaces and thus is readily excreted from organisms. It is vital to understand that there are many thousands of species which can be classified as PFAS and, although some indeed pose a threat to environmental health, some do not; TFA does not.