Endodontic failure caused by transportation, drilling, overfilling and failure to repair an injury apical sometimes lead to surgical therapy. With periapical surgery consisting of exposure of the apex, root resection and preparation of a cavity that is hermetically sealed, we will correct the persistent defects. The combination of this surgical technique with retrograde obturation provides high success rates. There are several widely used retrofilling materials, such as: IRM, Retroplast, SuperEBA or mineral trioxide aggregate (MTA) whick allow a retrograde sealing of the preparations. A case of a patient with recurrent apical lesion, describes the surgical technique of apicectomy and retrograde filling to preserve an upper lateral incisor with failed root canal retreatment and symptomatic persistent apical lesion.