The traceability of explosive devices in Ghana’s mining and construction industries is essential to ensuring safety and regulatory compliance, and preventing misuse, especially in combating illegal mining and terrorism-related activities in the sub-region. Despite existing regulations, the lack of an efficient and transparent tracking system has resulted in challenges, including the stealing and diversion of explosives for unauthorised use, posing significant risks to public safety and the environment. This study examines the current state of Explosive Device (ED) traceability in Ghana, identifying key challenges, including insufficient data management, limited technological infrastructure, and the prevalence of illegal small scale mining activities. This study proposes a multi-faceted approach to address these challenges, focusing on deploying and integrating a web-based Harmonised Explosive Management System for real-time inventory management, integrated with advanced technologies, such as invisible QR coding, as an added layer to enhance security. Additionally, this study highlights the importance of stakeholder collaboration, involving the government, regulatory bodies, and private sector stakeholders in the management of an integrated, efficient traceability system. Through these proposed solutions, this study aims to strengthen the monitoring and control of EDs in Ghana, ensuring that they are only used for their intended legitimate purposes while mitigating the risks associated with illegal activities and enhancing overall safety in the mining and construction sectors.