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Advance Research in Organic and Inorganic Chemistry
[ ISSN : 2833-3594 ]

Putative Receptors for Bacillus Thuringiensis Var. Israelensis Cry11Aa in Haemonchus Contortus Larvae

Research Article
Volume 2 - Issue 1 | Article DOI : 10.54026/AROIC/1002

Ana Paula de Souza Stori de Lara, Neida Lucia Conrad, Frederico Schmitt Kremer, Luciano da Siva Pi nto and Fábio Pereira Leivas Leite*

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Published : December 15, 2021

Abstract

Objectives: Through bioinformatics analysis, predict Haemonchus contortus larvae putative receptors for Cry11Aa. Results: Using a PyDOCK predicted high affinity interaction, as demonstrated by the highly negative binding energies of -57.2, -72.8, and -68.4 respectively for HC23, H-GAL-GP, H11, and all receptors docked to the domain II of Cry11Aa. Conclusion: These results suggest that Bti Cry11Aa toxin may use the proteins HC23, H-GAL-GP, and H11 as a receptor in Haemonchus contortus larvae and by doing so, carry out its nematicidal effect